Drug Standards
Medchemexpress LLC Felodipine | 72509-76-3 | 99.8% | 25 MG
Felodipine is a dihydropyridine, potent, and vasoselective calcium channel antagonist. It lowers blood pressure by selectively acting on vascular smooth muscle, especially in the resistance vessels. As an anti-hypertensive agent, Felodipine induces autophagy and can cross the blood-brain barrier.
- Potent, vasoselective calcium channel antagonist
- Lowers blood pressure
- Induces autophagy
- Can cross the blood-brain barrier
Medchemexpress LLC Triamcinolone (standard) | 124-94-7 | 98.02% | 25 MG
Triamcinolone (Standard) is the analytical standard of Triamcinolone, intended for research and analytical applications. It is commonly employed in qualitative, quantitative, and methodological research experiments.
- Used as a reference standard for assays
- Suitable for HPLC, GC, and MS techniques
- Molecular weight of 394.43 and chemical formula C₂₁H₂₇FO₆
- Appears as a solid with a white to off-white color
- Classified as a steroid
- Initial source from plants in the Solanaceae family
Medchemexpress LLC Amodiaquine impurity 1 | 81099-86-7 | 98.7% | 270.72 | 100 MG
Amodiaquine impurity 1 is a chemical substance used in laboratory research and the manufacture of other substances. This compound is identified as an impurity of Amodiaquine and typically appears as a solid.
- Used for laboratory research and manufacturing purposes
- Supplied as a solid
- Recommended storage at 4°C, protected from light, and under nitrogen
- In solvent, stable for 6 months at -80°C or 1 month at -20°C, protected from light and under nitrogen
Medchemexpress LLC Amodiaquine impurity 1 | 81099-86-7 | 270.72 | 500 MG
Amodiaquine impurity 1 is a chemical identified as an impurity of Amodiaquine. It is intended for research use only by experienced personnel in laboratory settings for the manufacture of substances. This product has not been fully validated for medical applications.
- Store at 4°C, protected from light, and under nitrogen.
- In solvent, store at -80°C for up to 6 months or -20°C for up to 1 month, protected from light and under nitrogen.
- Soluble in DMSO at 20 mg/mL (73.88 mM) with ultrasonic, warming, and heating to 60°C.
Medchemexpress LLC Ranitidine S-oxide | 73851-70-4 | 99.0% | 330.41 | 10 MG
Ranitidine S-oxide is a metabolite of Ranitidine, a potent, selective, and orally active histamine H2-receptor antagonist with an IC50 of 3.3 μM, which inhibits gastric secretion.
- Metabolite of Ranitidine.
- Acts as a histamine H2-receptor antagonist.
- Inhibits gastric secretion.
- Molecular weight is 330.41.
- Purity of 99.03%.
- Appears as a yellow to brown solid.
- Soluble in water at 125 mg/mL.
Medchemexpress LLC Clopidogrel impurity 1 | 120202-71-3 | 419.89 | 1 G
Clopidogrel impurity 1 is an impurity of Clopidogrel (HY-15283). It has a molecular formula of C16H18ClNO6S2 and a molecular weight of 419.89, with a CAS No. of 120202-71-3. It is classified as a Drug Intermediate and is intended for research use only.
- For research use only.
- Not sold to patients.
Medchemexpress LLC Benzarone | 1477-19-6 | 99.67% | 266.29 | 1 ML
Benzarone is an oral inhibitor of human urate transporter 1 (hURAT1) with an IC50 value of 2.8 μM, and it also acts as an uncoupler of oxidative phosphorylation. Benzarone can cause liver damage and promote cell apoptosis and necrosis. It can be used to lower serum uric acid levels and for research in vascular diseases.
- Oral inhibitor of human urate transporter 1 (hURAT1)
- IC50 value of 2.8 μM for hURAT1 in oocyte
- Acts as an uncoupler of oxidative phosphorylation
- Can cause liver damage and promote cell apoptosis and necrosis
- Used to lower serum uric acid levels
- Used for research in vascular diseases
Medchemexpress LLC Detomidine hydrochloride | 90038-01-0 | 99.8% | 5 G
Detomidine hydrochloride is an imidazole derivative and a potent α2-adrenergic agonist. It provides dose-dependent analgesic effects through the activation of α2 catecholamine receptors, leading to reduced production of excitatory neurotransmitters. This product also has cardiac, respiratory, and antidiuretic actions due to its inhibition of the sympathetic nervous system. It is currently licensed for use in horses.
- Potent α2-adrenergic agonist
- Provides dose-dependent analgesic effects
- Activates α2 catecholamine receptors
- Inhibits the sympathetic nervous system
- Exhibits cardiac, respiratory, and antidiuretic actions
- Licensed for use in horses
Medchemexpress LLC Sarafloxacin hydrochloride | 91296-87-6 | 98.13% | 5 G
Sarafloxacin hydrochloride is a quinolone antibiotic agent, effective against poultry diseases and *Edwardsiella ictaluri* infections in channel catfish. Its inhibitory levels vary by bacterial strain, with *Escherichia coli* isolates showing higher sensitivity in broth culture compared to simulated gut models, suggesting potential absorption to organic matter. In field trials, administration to catfish infected with *E. ictaluri* significantly improved survival rates.
- Quinolone antibiotic agent
- Effective against poultry diseases
- Successfully treated *Edwardsiella ictaluri* infections in channel catfish
- Demonstrated varying inhibitory levels for tested bacteria
- Improved survival rates in field trials for infected catfish
Medchemexpress LLC Bromhexine hydrochloride | 611-75-6 | 99.9% | 5 G
Bromhexine hydrochloride is a potent and specific TMPRSS2 protease inhibitor with an IC50 of 0.75 μM, which can help prevent and manage SARS-CoV-2 infection. It also functions as an autophagy agonist and a mucolytic cough suppressant, offering potential benefits for various respiratory conditions.
- Potent and specific TMPRSS2 protease inhibitor
- Helps prevent and manage SARS-CoV-2 infection
- Autophagy agonist
- Mucolytic cough suppressant
- Potential for various respiratory conditions
Medchemexpress LLC Idoxuridine | 54-42-2 | 99.95% | 10 G
Idoxuridine is an iodinated thymidine analogue that competitively inhibits phosphorylases. It demonstrates viral inhibitory activity, particularly against viral eye infections such as herpes simplex keratitis, by inhibiting DNA polymerase and disrupting viral replication.
- Competitively inhibits phosphorylases
- Inhibits viral activity, including herpes simplex keratitis
- Acts by inhibiting DNA polymerase
- Affects viral replication
- Displays anti-orthopoxvirus activity
- Can stimulate the production of hemolysin plaque-forming cells to sheep red blood cells in animal models
Medchemexpress LLC Triamcinolone | 124-94-7 | 99.8% | 1 G
Triamcinolone is a long-acting corticosteroid with anti-inflammatory, anti-oedematous, anti-proliferative, anti-angiogenetic, immunomodulatory, and neuroprotective effects. It works by binding to glucocorticoid receptors.
- Alleviates various dermatitis, immune diseases, and ocular diseases.
- Intended for research and analytical applications.
- Target: Glucocorticoid receptor, interleukin related.
- Research areas include: cardiovascular disease, inflammation/immunology, endocrinology, and cancer.
Medchemexpress LLC Amoxicillin | 26787-78-0 | ≥98.0% | 50 G
Amoxicillin, also known as Amoxycillin, is an antibiotic characterized by its good oral absorption and broad-spectrum antimicrobial activity. It operates by inhibiting the biosynthesis of polypeptides crucial for bacterial cell wall formation, which in turn effectively suppresses bacterial cell growth.
- Good oral absorption
- Broad-spectrum antimicrobial activity
- Inhibits biosynthesis of bacterial cell wall polypeptides
- Effective in suppressing bacterial cell growth
Medchemexpress LLC Diphenhydramine | 58-73-1 | 99.6% | 1 ML
Diphenhydramine is a first-generation histamine H1-receptor antagonist that also exhibits anti-cholinergic effects. This compound is known for its ability to cross the ovine blood-brain barrier (BBB) and can block NMDA-activated membrane currents, which may contribute to its sedative, analgesic, and memory-related effects.
- First-generation histamine H1-receptor antagonist
- Possesses anti-cholinergic effect
- Can cross the ovine blood-brain barrier
- Targets H1 receptor and NMDA receptor
- Blocks NMDA-activated membrane currents
- May improve kidney injury induced by cisplatin in mice
- Exhibits better oral bioavailability when combined with dimenhydrinate
Medchemexpress LLC Larotrectinib sulfate | 1223405-08-0 | 99.0% | 1 ML
Larotrectinib sulfate is an ATP-competitive oral, selective inhibitor of the tropomyosin-related kinase (TRK) family receptors, with low nanomolar 50% inhibitory concentrations against all three isoforms (TRKA, B, and C).
- ATP-competitive oral inhibitor
- Selective inhibitor of TRK family receptors (TRKA, B, and C)
- Low nanomolar 50% inhibitory concentrations against all three isoforms
- Greater than 1,000-fold selectivity relative to other kinases
- Demonstrates dose-dependent inhibition of cell proliferation
- Reduces tyrosine phosphorylation of TRKA and downstream signal transduction
- Well tolerated in GLP toxicology studies
- Reduces leukemic infiltration to undetectable levels in bone marrow and spleen